Objective: The subject of this research is the preparation and characterization of porous bioactive glasses (MBGs) by sol-gel method based on strontium (Sr2+) and Cobalt (Co2+) for tissue engineering strategies.
Main results: FTIR and XRD spectra were used to analyze MBGs and SEM showed a uniform distribution of spheres with minimal agglomeration or scattered clumps and the thermal behavior of the polymer was investigated by TGA. Paying attention to the antibacterial test results of MBGs showed that they show very good antibacterial properties against Candida albicans and Escherichia Coli bacteria, Staphylo Coccus aureus, and the lack of cytotoxicity Compared to Control sample has a higher potential and can to be used as a bone implant with antibacterial properties in bone tissue engineering applications.
Important Conclusion: Sr2+ and Co2+ were Cosubstituted in MBGs to develop osteogenic potential and antibacterial properties without changing the size, morphology, negative surface charge, amorphous nature, porous structure and pore size.
Type of Study:
Research |
Subject:
Bioceramics Received: 2024/12/12 | Accepted: 2025/01/19